Plasma rich in growth factors (PRGF-Endoret) in the treatment of symptomatic knee osteoarthritis: a randomized clinical trial

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A randomized clinical trial evaluating plasma rich in growth factors (PRGF-Endoret) versus hyaluronic acid in the short-term treatment of symptomatic knee osteoarthritis.

PURPOSE This multicenter, double-blind clinical trial evaluated and compared the efficacy and safety of PRGF-Endoret (BTI Biotechnology Institute, Vitoria-Gasteiz, Spain), an autologous biological therapy for regenerative purposes, versus hyaluronic acid (HA) as a short-term treatment for knee pain from osteoarthritis. METHODS We randomly assigned 176 patients with symptomatic knee osteoarthr...

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ژورنال

عنوان ژورنال: Osteoarthritis and Cartilage

سال: 2012

ISSN: 1063-4584

DOI: 10.1016/j.joca.2012.02.260